博士生导师  硕士生导师

徐甲坤，男，1984年1月生人，于2011年9月获日本名古屋大学生物无机化学专业博士学位，现任中国水产科学研究院黄海水产研究所科研处副处长，研究员，研究生导师。主要从事生物催化与转化等方面的研究，主持国家自然科学基金（面上、青年）、科技部“高端外国专家引进计划”项目、农业农村部农业国际交流合作项目、山东省重点研发计划等10余项项目；在ACS Catalysis、Journal of Hazardous Materials、Biosensors and Bioelectronics、International Journal of Biological Macromolecules、Catalysis Science&Technology、Chemistry–A European Journal等国际知名期刊发表论文60余篇，其中第一/通讯作者SCI 40余篇；获授权国家发明专利10余项（第一发明人6项）；主编副主编出版著作3部；入选中国水产科学研究院“百名英才培育计划”、中国水产科学研究院“青年英才”拔尖人才，荣获山东省海洋与渔业科学技术奖青年科技奖、中国水产科学研究院黄海水产研究所青年科技奖；担任中国水产科学研究院海洋生物酶工程创新团队副首席；兼任亚太水产养殖中心网（NACA）技术指导委员会委员、中国水产学会海水养殖分会秘书长、中国海洋大学校友高级专家协会副秘书长，山东大学、中国海洋大学、上海海洋大学、青岛科技大学等高校研究生导师。

联系电话：13869828530，0532-85812670

通讯地址：山东省青岛市市南区南京路106号

邮政编码：266071

E-mail：xujk@ysfri.ac.cn

代表性论著：

1. Ridong Yang, Osami Shoji, Yingwu Lin, Fang Wang, Hongxia Che, Jiakun Xu^*, Construction of P450 scaffold biocatalysts for the biodegradation of five chloroanilines， Journal of Hazardous Materials, 2025, 488, 137305.

2.Yadan Yang, Weikang Zhang, Fang Wang, Dong Li, Xiangmin Meng, Xiaochun Sun, Jiakun Xu*, Construction of biocatalysts based on P450BM3 for the degradation of non-steroidal anti-inflammatory drugs, Journal of Hazardous Materials, 2024, 480, 136097.

3. Weikang Zhang, Yingwu Lin, Xiangmin Meng, Qiaoning Wang, Lingxin Chen*, Jiakun Xu^*, Construction of a myoglobin scaffold-based biocatalyst for the biodegradation of sulfadiazine and sulfathiazole, Journal of Hazardous Materials, 2024, 465, 113147.

4. Sijia Zhao, Yingwu Lin, Jinghan Wang, Dong Li, Fang Wang, Osami Shoji, Jiakun Xu^*, Regioselective aromatic O-demethylation with an artificial P450BM3/sugar alcohol oxidase peroxygenase system, International Journal of Biological Macromolecules, 2025, 309, 142768.

5. Weikang Zhang, Yadan Yang, Xiangmin Meng,*, Fang Wang, Yingwu Lin*, Jiakun Xu^*, Construction of artificial peroxidase based on myoglobin scaffold for efficient degradation of meloxicam, Journal of Inorganic Biochemistry, 2025, 262, 112733.

6. Guangrong Wu, Jiakun Xu^*, Lijuan Sun, Yingfu Li, Shuqin Gao, Yingwu Lin^*, Application of engineered heme enzymes based on myoglobin with high peroxidase activity for efficient degradation of various emerging pollutants, Journal of Environmental Chemical Engineering, 2023, 11, 111471.

7. Bin Qiao^*, Jiakun Xu^*, Wenhao Yin, Wanmeng Xin, Lixin Ma, Jie Qiao^*, Yi Liu^*, “Aptamer-locker” DNA coupling with CRISPR/Cas12a-guided biosensing for high-efficiency melamine analysis, Biosensors and Bioelectronics, 2021, 183, 113233.

8. Yihui Jiang, Chunlan Wang, Nana Ma, Jie Chen, Chuanfei Liu, Fang Wang, Jiakun Xu^*, Zhiqi Cong^*, Regioselective aromatic O-demethylation with an artificial P450BM3 peroxygenase system, Catalysis Science &Technology, 2020, 10, 1219-1223.

9. Jiakun Xu, Chunlan Wang, Zhiqi Cong^*, Strategies for substrate-regulated p450 catalysis: from substrate engineering to co-catalysis, Chemistry–A European Journal, 2019, 25, 6853-6863.